apalutamide will reduce the extent or result of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Coadministration of apalutamide, a solid CYP3A4 inducer, with drugs which are CYP3A4 substrates can lead to lower publicity to those remedies.Some industry experts suggest Xanax to be used with caution as i… Read More